General Cell Based Assays
Abcam Calcium Assay kit (Fluorometric)
Calcium Assay kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress mAGTRL1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0565E2MCP0M)
The PathHunter mAGTRL1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. apelin-13) based activation of mAGTRL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mAGTRL1 and EA-tagged β-Arrestin-2. Activation of mAGTRL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam JC 10 Mitochondrial Membrane Potential Assay Kit (Flow Cytometry)
JC 10 Mitochondrial Membrane Potential Assay Kit (Flow Cytometry)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress P2RY4 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0263E2CP0L)
The PathHunter P2RY4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. UTP) based activation of P2RY4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged P2RY4 and EA-tagged β-Arrestin-2. Activation of P2RY4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ILEX LIFE SCIENCES LLC QuickZyme Sensitive Tissue Collagen Assay Kit, 96 Assays, 96-well plate format, colorimetric assay for low level collagen analysis (tissue, tissue homogenates samples)
QuickZyme Sensitive Tissue Collagen Assay Kit enables collagen analysis in small tissue samples with low collagen levels. The assay is based on quantitative colorimetric determination of hydroxyproline residues, obtained by acid hydrolysis of collagen. The assay allows quantitative measurement of all types of collagen, species independent. The only hydroxyproline-based assay which shows no matrix effect and no need for further dilution of hydrolysate. No drying of hydrolysate is needed, resulting in a fast and easy (96-well plate format) assay. Application: tissues with low collagen/hydroxyproline content (ex. liver). Sensitivity: 2.4 µM (0.3 µg/ml). Assay-time: < 2 hours. Collagen is a main component of extracellular matrix. Dysregulation in collagen production results in pathologies such as fibrosis (too much collagen), or osteoarthritis (too little collagen). Thus measurement of collagen production is important in many disease related studies.
Eurofins Discoverx PathHunter eXpress CCR2 Total GPCR Internalization Assay, 2pl Kit. (93-0679E3CP5M)
The PathHunter CCR2 Total GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of CCR2 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged CCR2 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the CCR2 receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mINSRa Functional Assay, 2-Plate Kit. (93-1015E3CP16M)
The PathHunter eXpress mINSRa Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated mINSRa dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged mINSRa and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of the protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Oncoimmunin Inc GRANTOXILUX-PLUS kit, fluorogenic cytotoxicity assay, green substrate, 80 assays per kit, 2,000-10,000 target cells, 30 min to 2 hours incubation
GRANTOXILUX-PLUS kit, fluorogenic cytotoxicity assay, green substrate, 80 assays per kit, 2,000-10,000 target cells, 30 min to 2 hours incubation
Eurofins Discoverx PathHunter eXpress KDR/KDR Dimerization Assay, 2-Plate Kit. (93-0996E1CP0M)
The PathHunter KDR/KDR Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. VEGF-121) induced dimerization of KDR/KDR receptors. This product uses EFC technology. The cell line included overexpresses KDR target protein fused to PK alongside KDR target protein fused to EA. Upon ligand-induced dimerization of KDR/KDR, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress CHRM1 U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0859E3CP0L)
The PathHunter CHRM1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. acetylcholine) based activation of CHRM1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CHRM1 and EA-tagged β-Arrestin-2. Activation of CHRM1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter BDKRB2 Bioassay Kit, 2-Plate. (93-0189Y2-00113)
The PathHunter BDKRB2 Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. bradykinin) based activation of BDKRB2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged BDKRB2 and EA-tagged β-Arrestin-2. Activation of BDKRB2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Meso Scale Discovery R-PLEX Human IL-24 ASY
The R-PLEX Human IL-24 Assay QuickPlex 5-PL Kit from Meso Scale Diagnostics is a multiplex immunoassay kit for the quantitative measurement of human Interleukin 24 (IL-24) in serum plasma and cell culture supernatants The kit utilizes electrochemiluminescence (ECL) detection technology and provides reagents for 5-plex analysis of IL-24 in a quick and streamlined workflow The assay has high sensitivity wide dynamic range and requires low sample volume This product can aid in cytokine profiling and research related to cancer and inflammatory conditions
Eurofins Discoverx cAMP Hunter eXpress PTHR2 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0057E2CP2L)
The cAMP Hunter PTHR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. parathyroid hormone, TIP 39) based activation of PTHR2 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type PTHR2, a naturally Gs coupled GPCR. Upon activation of PTHR2, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Miltenyi Biotec, Inc. mIFN-g Secr.Assay Enrichm.&Det.Kit(PE)
Isolation and detection of mouse IFN-γ–secreting cells.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
Eurofins Discoverx PathHunter Human PTGER2 β-Arrestin Cell-Based Assay Kit (HEK 293)
The PathHunter Human PTGER2 β-Arrestin Stable Cell Line Assay (HEK 293) contains a stable clonal cell line used to measure PTGER2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.